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Posts Tagged ‘nephropathy’

SUMMARY:

This is a review on diabetic nephropathy, including its history, genetics, incidence, pathophysiology, treatment and kidney transplantation – pancreas.

We recommend appropriate prevention and awareness of this entity to reduce its incidence and severity.

INTRODUCTION

Insulin-dependent diabetes mellitus develops mainly in children and young adults but can occur at any age group. Its incidence rate varies from 30 – 35 per 100 000 inhabitants in Finland and Sardinia, to very low rates in eastern populations. The diagnosis is more common in winter months and their susceptibility is associated with HLA on chromosome 6, interacting with environmental factors (virus, food and climate) as well as immune processes leading to beta cell destruction. Read the rest of this entry »

Chronic renal failure is the slow, progressive decline in renal function. It is usually a complication of another disease. Unlike acute renal failure, which happens quickly and suddenly, chronic failure happens gradually – for weeks, months or years – as the kidneys slowly stop working, which leads to renal disease (ESRD).

The progression is so slow that the disease can remain silent until significant damage is done. United States, about one in 1000 is treated for ESRD and more than 19 million adults live with some form of chronic renal failure. In Canada, about 1.9 to 2.3 million people are suffering from chronic renal failure. Read the rest of this entry »